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Untargeted metabolomics In brief, extracted cellular metabolites were analyzed in one batch along with technical quality control (TQC) samples spaced 1 in every 10

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Myelin sheath integrity critical for nerve signal transmission is partially B12-dependent

First, they need to be well-detailed mechanistic studies that disentangle causal relationships between specific microbes and neurological outcomes rather than mere correlational evidence that would lead to therapeutic targets

This reagent provides a colorimetric readout when it binds to exposed free thiols, thereby detecting the lipoate moiety if an adduct is removed (Fig

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